CHEMBL3798754


SMILES Cc1ccc(-c2nc(N)c3nn(Cc4ccccc4)cc3n2)o1
InChIKey WXADNPIZOQQAEO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 305.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Human Adenosine A pKi 8.04 8.04 8.04 ChEMBL
A1 AA1R Human Adenosine A pKi 6.87 6.87 6.87 ChEMBL
A3 AA3R Human Adenosine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Human Adenosine A pIC50 7.96 7.96 7.96 ChEMBL
A1 AA1R Human Adenosine A pIC50 6.82 6.82 6.82 ChEMBL