CHEMBL3800633


SMILES CN(CCCCNC(=O)c1cc2ccccc2o1)[C@@H]1Cc2cccc3[nH]c(=O)n(c23)C1
InChIKey FGHOMVBEDZJTLR-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 418.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 5.58 6.08 6.59 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.83 6.32 7.81 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 6.94 7.33 7.71 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.68 7.14 7.71 ChEMBL