Chembl3823231


SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCN(C(=O)C2CC2)c2ccc(Cc3ccccc3)cc21
InChIKey DJFAPAQDMDGGSM-WUFINQPMSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 497.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Rat Opioid A pKi 9.46 9.46 9.46 ChEMBL
δ OPRD Rat Opioid A pEC50 8.0 8.0 8.0 ChEMBL
μ OPRM Rat Opioid A pKi 10.0 10.0 10.0 ChEMBL
μ OPRM Rat Opioid A pEC50 8.74 8.74 8.74 ChEMBL
κ OPRK Human Opioid A pKi 7.6 7.6 7.6 ChEMBL
κ OPRK Human Opioid A pEC50 6.0 6.0 6.0 ChEMBL