CHEMBL3818994


SMILES O=C(CCCN1CCc2ccccc2C1)c1ccc(F)cc1
InChIKey NMALCZJKSYZTRE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 297.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.64 8.64 8.64 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
H1 HRH1 Human Histamine A pKi 7.06 7.06 7.06 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.85 7.85 7.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.14 7.14 7.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.31 7.31 7.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database