CHEMBL3819153


SMILES O=c1[nH]c2cc(Cl)ccc2n1C1CCN(CCCCc2nc3ccccc3o2)CC1
InChIKey RILXDJGPJCVJME-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
H1 HRH1 Human Histamine A pKi 6.29 6.29 6.3 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.08 6.08 6.08 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.47 5.47 5.47 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.02 7.02 7.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database