CHEMBL381717
SMILES | CN(C)CCCOc1ccc(CN2CCCCC2)cc1 |
InChIKey | QUUUOVGZDVVVGL-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 0 |
Rotatable bonds | 7 |
Molecular weight (Da) | 276.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Guinea pig | Histamine | A | pKi | 7.48 | 7.48 | 7.48 | ChEMBL |
H3 | HRH3 | Guinea pig | Histamine | A | pKd | 7.5 | 7.5 | 7.5 | ChEMBL |
H3 | HRH3 | Rat | Histamine | A | pKi | 7.35 | 7.35 | 7.35 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKd | 8.03 | 8.03 | 8.03 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 8.52 | 8.52 | 8.52 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |