CHEMBL3817898


SMILES COc1ccc(C(=O)CCCN2CCc3ccccc3C2)cc1
InChIKey SQGWMVXOYSHVTI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 309.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.68 6.68 6.68 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.85 5.85 5.85 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.77 7.77 7.77 ChEMBL
H1 HRH1 Human Histamine A pKi 6.67 6.69 6.7 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.42 7.42 7.42 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.52 5.59 5.67 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.54 7.59 7.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.6 6.6 6.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database