CDPPB


SMILES N#Cc1cccc(c1)C(=O)Nc1cc(nn1c1ccccc1)c1ccccc1
InChIKey BKUIZWILNWHFHD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 364.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations mGlu5

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BB2 GRPR Human Bombesin A pKi 6.67 6.72 6.77 Guide to Pharmacology
BB2 GRPR Rat Bombesin A pKi 5.0 5.0 5.0 Guide to Pharmacology
BB1 NMBR Rat Bombesin A pKi 6.66 6.94 7.23 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BB1 NMBR Human Bombesin A pIC50 6.22 6.39 6.56 Guide to Pharmacology
BB2 GRPR Human Bombesin A pIC50 5.34 5.47 5.61 Guide to Pharmacology
BB3 BRS3 Human Bombesin A pIC50 5.6 5.6 5.6 Guide to Pharmacology
BB1 NMBR Rat Bombesin A pIC50 6.0 6.0 6.0 Guide to Pharmacology