CHEMBL3891231


SMILES COc1cc(Nc2ccc(S(=O)(=O)NCC3CC3)c(C(F)(F)F)c2)cc(OC)c1
InChIKey PXRZBSVMVTXTQV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 430.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 5.81 6.18 6.58 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 7.43 7.54 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pIC50 5.51 5.9 6.24 ChEMBL
CB2 CNR2 Human Cannabinoid A pIC50 7.12 7.24 7.43 ChEMBL