CHEMBL373695


SMILES CC(C)c1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNC[C@@H]21
InChIKey XZWBTHWEZHVQCP-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 298.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.72 6.72 6.72 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.29 7.29 7.29 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.58 5.58 5.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.14 7.14 7.14 ChEMBL