CHEMBL373873


SMILES Cc1c(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)nnn1Cc1ccccc1
InChIKey AARWRAFDYZSYPD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 500.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.55 6.55 6.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.37 8.37 8.37 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.13 8.13 8.13 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.41 7.63 7.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database