CHEMBL3739745


SMILES CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cnn(C)c2)CC1
InChIKey DHICCJDVBYVTJF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 406.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.19 6.19 6.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database