CHEMBL3752270


SMILES CN1CCN(c2nc(NCc3ccccc3)nc3c2CCc2ccccc2-3)CC1
InChIKey XYWXZLNTBBSVNH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 385.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 5.8 5.8 5.8 ChEMBL
H2 HRH2 Human Histamine A pKi 5.16 5.16 5.16 ChEMBL
H1 HRH1 Human Histamine A pKi 5.68 5.68 5.68 ChEMBL
H3 HRH3 Human Histamine A pKi 5.22 5.22 5.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 6.03 6.03 6.03 ChEMBL