CHEMBL3906408


SMILES O=C(CCCCCN1CCN(c2ccccc2-c2ccccc2)CC1)NCc1ccc(OCCCN2CCOCC2)cc1
InChIKey HCQHYAXNIILCGJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 15
Molecular weight (Da) 584.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.02 8.02 8.02 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.94 5.94 5.94 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database