CHEMBL3759160


SMILES COc1ccc2ccc3occ(CNC(=O)CF)c3c2c1
InChIKey RVGXXLUBJYLHSV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 287.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pKi 8.68 8.68 8.68 ChEMBL
MT1 MTR1A Human Melatonin A pKi 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pEC50 8.47 8.47 8.47 ChEMBL
MT1 MTR1A Human Melatonin A pEC50 7.54 7.54 7.54 ChEMBL