ARMODAFINIL


SMILES NC(=O)C[S@@+]([O-])C(c1ccccc1)c1ccccc1
InChIKey YFGHCGITMMYXAQ-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 273.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 4.41 4.41 4.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.36 8.36 8.36 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 8.16 8.16 8.16 Drug Central
D2 DRD2 Human Dopamine A pIC50 8.68 8.68 8.68 ChEMBL