ARMODAFINIL
SMILES | NC(=O)C[S@@+]([O-])C(c1ccccc1)c1ccccc1 |
InChIKey | YFGHCGITMMYXAQ-LJQANCHMSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 1 |
Rotatable bonds | 5 |
Molecular weight (Da) | 273.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D3 | DRD3 | Human | Dopamine | A | pKi | 4.41 | 4.41 | 4.41 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 8.36 | 8.36 | 8.36 | Drug Central |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D2 | DRD2 | Human | Dopamine | A | pEC50 | 8.16 | 8.16 | 8.16 | Drug Central |
D2 | DRD2 | Human | Dopamine | A | pIC50 | 8.68 | 8.68 | 8.68 | ChEMBL |