CHEMBL3765876


SMILES O=C(CCCCCN1CCN(c2ccccc2O)CC1)n1c2ccccc2c2ccccc21
InChIKey DTJJOPFHDLSVKA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 441.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.03 6.03 6.03 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.55 7.55 7.55 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.42 7.42 7.42 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.86 5.86 5.86 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database