CHEMBL377935


SMILES Cc1cccc(NC(=O)c2cccc(-c3ccccc3)c2)n1
InChIKey WRRMPYACQDSPSL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 288.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 5.14 5.14 5.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 5.14 5.14 5.14 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 4.74 4.74 4.74 ChEMBL