CHEMBL3779931


SMILES CCn1cc(C[C@H](NC(=O)[C@@H]2CCC(=O)N2)C(=O)N2CCC[C@H]2C(N)=O)nc1Br
InChIKey INHQNOSKEMHHAM-AVGNSLFASA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 468.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TRH1 TRHR Mouse Thyrotropin-releasing hormone A pIC50 4.73 4.73 4.73 ChEMBL
TRH1 TRHR Mouse Thyrotropin-releasing hormone A pEC50 5.74 6.83 7.92 ChEMBL