Chembl3922780


SMILES COc1ccc2c(c1)[C@]13CCN(CC4CC4)[C@H](C2)[C@]1(O)C[C@H](CCO)C(=O)C3
InChIKey WCTMMHOXMUBVQK-XCYUPCBOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 385.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 6.4 6.4 6.4 ChEMBL
κ OPRK Human Opioid A pEC50 5.99 5.99 5.99 ChEMBL
μ OPRM Human Opioid A pKi 6.23 6.23 6.23 ChEMBL
μ OPRM Human Opioid A pEC50 6.39 6.39 6.39 ChEMBL