Chembl3927136


SMILES CC[C@H](C)[C@H](N)C(=O)OC[C@H]1C[C@@]23CC[C@]1(OC)[C@@H]1Oc4c(O)ccc5c4[C@@]12CCN(CC1CC1)[C@@H]3C5
InChIKey AGUKEFSLHJXTQC-WLQXWTRFSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 510.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 10.22 10.22 10.22 ChEMBL
κ OPRK Human Opioid A pEC50 9.02 9.02 9.02 ChEMBL
μ OPRM Human Opioid A pKi 9.82 9.82 9.82 ChEMBL
μ OPRM Human Opioid A pEC50 8.3 8.3 8.3 ChEMBL