Chembl3927726

Chemical Properties

SMILES CCc1nc(C(F)(F)F)cnc1N[C@H]1CCC[C@@H]1NC(=O)c1ccccc1-n1nccn1
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight 445.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey RRFVHLBWQUXKCB-HOTGVXAUSA-N

Database Connections

External Links

Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pIC50 7.47 7.47 7.47 ChEMBL