Chembl3930729


SMILES CCOC(=O)CC[C@H]1[C@H](COCc2ccccc2)[C@@]23CC[C@]1(OC)[C@@H]1Oc4c(OC)ccc5c4[C@@]12CCN(CC1CC1)[C@@H]3C5
InChIKey USFPJCSJMBKHLN-JLWDJLIZSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 12
Molecular weight (Da) 601.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 8.59 8.59 8.59 ChEMBL
κ OPRK Human Opioid A pEC50 6.89 6.89 6.89 ChEMBL
μ OPRM Human Opioid A pKi 7.61 7.61 7.61 ChEMBL
μ OPRM Human Opioid A pEC50 6.73 6.73 6.73 ChEMBL