CHEMBL393365


SMILES C#Cc1ccc(C(=O)NCCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)cc1
InChIKey VMOFYGZGNSIHPR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 443.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.11 6.11 6.11 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.16 7.16 7.16 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.82 8.82 8.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.64 7.8 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database