CHEMBL3819567


SMILES O=C1NCN(c2ccccc2)C12CCN(CCCCc1nc3ccccc3s1)CC2
InChIKey AVKICTLBRHZUTM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 420.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
H1 HRH1 Human Histamine A pKi 6.3 7.62 8.93 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.88 6.88 6.88 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.49 7.5 7.5 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.62 7.62 7.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database