CHEMBL3819731


SMILES Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
InChIKey LEKOXFCRANACFL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 283.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.8 6.8 6.8 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.35 5.38 5.4 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
H1 HRH1 Human Histamine A pKi 6.13 6.13 6.13 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.22 5.22 5.22 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.85 6.85 6.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.5 6.5 6.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database