CHEMBL383484


SMILES CC(=O)c1cc(S(C)(=O)=O)cc2c3c(n(Cc4ccc(Cl)cc4)c12)[C@@H](CC(=O)O)CC3
InChIKey YYVOCPXSWUYWAL-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 459.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pKi 8.59 8.59 8.59 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 6.64 6.64 6.64 ChEMBL
TP TA2R Human Prostanoid A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pIC50 8.1 8.4 8.7 ChEMBL
TP TA2R Human Prostanoid A pIC50 5.08 5.08 5.08 ChEMBL