CHEMBL394110


SMILES O=C1c2ccccc2S(=O)(=O)N1CCCCN1CCN(c2ccccc2)CC1
InChIKey TWQROZICHMTHNN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 399.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.79 6.0 6.41 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.87 6.87 6.87 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.18 7.18 7.18 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.42 7.74 8.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database