CHEMBL394292


SMILES C#Cc1ccc(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)cc1
InChIKey WOZSFGJKUOKIMV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 429.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.04 6.04 6.04 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.51 9.51 9.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.57 7.7 7.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 8.7 8.7 8.7 ChEMBL