Ligand Data

Ligand

id 1487
Name eticlopride
SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(c1OC)Cl
InChIKey AADCDMQTJNYOSS-LBPRGKRZSA-N
Type small-molecule
External Links
Structure pdb 3PBL
Ligand site mutations D1 D2 D3 D4

Structure

Properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight 340.2

Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
D2 DRD2 Rat Dopamine A (Rhodopsin) 0.1 0.5 1.0
D3 DRD3 Human Dopamine A (Rhodopsin) 0.1 0.1 0.1
D2 DRD2 Human Dopamine A (Rhodopsin) 0.3 0.3 0.3