Chembl3958060

Chemical Properties

SMILES O=C1N[C@H](c2cncc(C#CC3CCOCC3)c2)[C@@H](c2cccc(F)c2)O1
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight 366.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey WFKCGVHRMKSZEI-WOJBJXKFSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 6.43 6.43 6.43 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 7.11 7.11 7.11 ChEMBL