Chembl397035


SMILES O=C(Nc1ccccc1)Oc1ccc2c(c1)C13CCCCC1C(C2)N(CC1CC1)CC3
InChIKey PNQVNINMHSUQSR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 416.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.8 8.8 8.8 ChEMBL
κ OPRK Human Opioid A pKi 10.34 10.34 10.34 ChEMBL
κ OPRK Human Opioid A pEC50 9.42 9.42 9.42 ChEMBL
μ OPRM Human Opioid A pKi 9.96 9.96 9.96 ChEMBL
μ OPRM Human Opioid A pEC50 9.36 9.36 9.36 ChEMBL
μ OPRM Human Opioid A pIC50 8.19 8.19 8.19 ChEMBL