Chembl3976681


SMILES COc1ccc2c(c1)[C@]13CCN(CC4CC4)[C@H](C2)[C@@H]1C[C@@H](C(C)C)C(=O)C3
InChIKey UASZQZJXTOBNEL-FMRHZRETSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 367.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 7.08 7.08 7.08 ChEMBL
κ OPRK Human Opioid A pEC50 5.98 6.25 6.52 ChEMBL
μ OPRM Human Opioid A pKi 6.32 6.32 6.32 ChEMBL
μ OPRM Human Opioid A pEC50 6.57 6.62 6.67 ChEMBL