CHEMBL1094807


SMILES FCCOCCO/N=C1/C=C(C#Cc2ccccn2)CCC1
InChIKey IKBQPNVYXHKVJS-LVZFUZTISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 302.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKd 7.86 8.54 9.22 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database