Chembl401278


SMILES C[C@H]1C2Cc3ccc(C(=O)NCCc4cccc(-c5ccccc5)c4)cc3[C@@]1(C)CCN2CC1CC1
InChIKey FXAPPSUTMKSLEJ-CHCCDMOGSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 478.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.23 8.23 8.23 ChEMBL
δ OPRD Human Opioid A pEC50 7.75 7.75 7.75 ChEMBL
κ OPRK Human Opioid A pKi 8.66 8.66 8.66 ChEMBL
κ OPRK Human Opioid A pEC50 7.92 7.92 7.92 ChEMBL
μ OPRM Human Opioid A pKi 9.02 9.02 9.02 ChEMBL
μ OPRM Human Opioid A pEC50 8.17 8.17 8.17 ChEMBL