CHEMBL3931889


SMILES COc1ccccc1-c1cc(CN(C)C)ccc1Cl
InChIKey GROYHNLGVCIQOI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 275.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 5.39 5.39 5.39 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.66 6.66 6.66 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.89 5.89 5.89 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.7 7.73 7.75 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.36 6.36 6.36 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.96 7.96 7.96 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.68 5.68 5.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pEC50 5.94 6.13 6.32 ChEMBL