CHEMBL4061334


SMILES Oc1ccc2c(c1)C13CCN(CC4CC4)C(C2)C12CCC1C3[C@@H](CN1Cc1ccccc1)C2
InChIKey RMSCVXDJUOMICG-SWBXKLIHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 440.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 8.37 8.37 8.37 ChEMBL
μ OPRM Human Opioid A pKi 8.46 8.46 8.46 ChEMBL
δ OPRD Human Opioid A pKi 9.23 9.23 9.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 8.35 8.35 8.35 ChEMBL
δ OPRD Human Opioid A pEC50 9.38 9.38 9.38 ChEMBL