CHEMBL1221499


SMILES COc1ccccc1N1CCN(CCNS(=O)(=O)c2ccc3ccccc3c2)CC1
InChIKey RQEBRILFCMJWAD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 6.46 6.46 6.46 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.29 8.29 8.29 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.61 7.61 7.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database