CHEMBL1221592


SMILES COc1ccccc1N1CCN(CCCCCNS(=O)(=O)c2ccc3ccccc3c2)CC1
InChIKey NADZGFHXOOQKNN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 467.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.08 7.08 7.08 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.07 8.07 8.07 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.56 7.56 7.56 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.36 6.36 6.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database