CHEMBL4065490
SMILES | CO[C@@]12CCC[C@@H]3Oc4c(O)ccc5c4[C@@]31CCN(C)[C@@H]2C5 |
InChIKey | RBHBHDMQEQBLQT-LTCOOKNTSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 1 |
Rotatable bonds | 1 |
Molecular weight (Da) | 301.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
δ | OPRD | Human | Opioid | A | pKi | 8.06 | 8.06 | 8.06 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 8.4 | 8.4 | 8.4 | ChEMBL |
μ | OPRM | Human | Opioid | A | pKi | 9.62 | 9.62 | 9.62 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
μ | OPRM | Human | Opioid | A | pEC50 | 8.86 | 8.86 | 8.86 | ChEMBL |