Chembl4077430


SMILES CN[C@@H]1Cc2cccc3c2n(c(=O)n3CCCCOc2ccc3c(c2)NC(=O)CC3)C1
InChIKey ZJCPSCHGZIVAIV-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 420.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 5.87 5.87 5.87 ChEMBL
D2 DRD2 Human Dopamine A pEC50 5.82 6.39 6.98 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.47 6.47 6.47 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.39 5.39 5.39 ChEMBL