CHEMBL4069251


SMILES N[C@@]1(C(=O)O)C[C@H](NC(=O)CCc2ccccc2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey MHGNPCZGYOTMGN-OTUNNCPPSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 332.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.55 6.55 6.55 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.22 6.22 6.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.69 5.69 5.69 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 5.26 5.26 5.26 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.05 6.05 6.05 ChEMBL