CHEMBL4076129


SMILES CN[C@@H]1Cc2cccc3c2n(c(=O)n3CCCCCCCCCCOCCCCc2ccccc2)C1
InChIKey HEHAZZLOEUQBDS-MUUNZHRXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 17
Molecular weight (Da) 491.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.95 6.95 6.95 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.62 7.62 7.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 5.6 5.88 6.15 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.35 5.72 6.1 ChEMBL