CHEMBL1098047


SMILES Cc1cc(C)cc([C@@H](CC(C)C)NC(=O)c2cc(Nc3cccc(C#N)c3)ccc2CCC(=O)O)c1
InChIKey YRZUQVSDZQNFBE-MUUNZHRXSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 483.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Mouse Prostanoid A pKi 5.06 5.06 5.06 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 6.66 6.66 6.66 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 9.44 9.44 9.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Mouse Prostanoid A pIC50 8.31 8.31 8.31 ChEMBL