CHEMBL4076303


SMILES CN1CCC23c4cc(O)ccc4CC1C21CCC2C3[C@@H](CN2C(=O)c2ccccc2)O1
InChIKey SFNHWRUBLKGHQX-NMBNTWCXSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 416.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 9.42 9.42 9.42 ChEMBL
δ OPRD Mouse Opioid A pKi 9.52 9.52 9.52 ChEMBL
κ OPRK Guinea pig Opioid A pKi 7.5 7.5 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 9.37 9.37 9.37 ChEMBL
κ OPRK Human Opioid A pEC50 7.3 7.3 7.3 ChEMBL
μ OPRM Human Opioid A pEC50 8.23 8.23 8.23 ChEMBL