CHEMBL3955128


SMILES CCCCC[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCCCCC(=O)O
InChIKey PWZMQIUUWBQDQW-WFPWZJHXSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 13
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 6.48 6.48 6.48 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 6.46 6.46 6.46 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 9.68 9.69 9.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 5.64 6.17 6.69 ChEMBL
EP4 PE2R4 Human Prostanoid A pIC50 9.24 9.24 9.24 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 9.43 9.95 10.68 ChEMBL