CHEMBL395933


SMILES O=C1Cc2ccccc2N1CCCCN1CCN(c2ccccc2)CC1
InChIKey LNEVPGGCVOGZMM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.5 6.5 6.5 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.13 7.13 7.13 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.1 7.1 7.1 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.79 6.8 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database