Chembl4095452


SMILES CN[C@@H]1Cc2cccc3c2n(c(=O)n3CCOCCOCCOCCOc2ccc3c(c2)NC(=O)CC3)C1
InChIKey YALCLPZHBNPXEN-JOCHJYFZSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 14
Molecular weight (Da) 524.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
D2 DRD2 Human Dopamine A pEC50 5.4 5.78 6.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.51 6.51 6.51 ChEMBL