CHEMBL4091231
SMILES | O=C1CCc2ccccc2N1CCCN1CCC(c2ccccc2)CC1 |
InChIKey | CDAYEBKMDIJVNY-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 0 |
Rotatable bonds | 5 |
Molecular weight (Da) | 348.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
M5 | ACM5 | Human | Acetylcholine (muscarinic) | A | pKi | 5.69 | 5.69 | 5.69 | ChEMBL |
M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pKi | 5.89 | 5.89 | 5.89 | ChEMBL |
M3 | ACM3 | Human | Acetylcholine (muscarinic) | A | pKi | 5.33 | 5.33 | 5.33 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 8.71 | 8.71 | 8.71 | ChEMBL |
M2 | ACM2 | Human | Acetylcholine (muscarinic) | A | pKi | 5.62 | 5.62 | 5.62 | ChEMBL |
M1 | ACM1 | Human | Acetylcholine (muscarinic) | A | pKi | 5.54 | 5.54 | 5.54 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.15 | 6.15 | 6.15 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.34 | 6.34 | 6.34 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |