Chembl4100734


SMILES CN[C@@H]1Cc2cccc3c2n(c(=O)n3CCCCCCCCCCCCOc2ccc3c(c2)NC(=O)CC3)C1
InChIKey DNLVWUGWSPNABX-AREMUKBSSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 15
Molecular weight (Da) 532.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.22 6.22 6.22 ChEMBL
D2 DRD2 Human Dopamine A pEC50 5.84 6.09 6.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.55 6.55 6.55 ChEMBL